Complex CDK2:CyclinE* map
Complex composition:

  1. CDK2 map
  2. CyclinE* map

(CDK2|​T160_pho:​CyclinE*)|​active@default

Identifiers
NAME:CDK2:CyclinE*

Maps_Modules
 dnarepair  map

References
d_re115( dnarepair  map ):
PMID:16581787,
For inhibition of S-checkpoint by ATM:
PMID:15175241
Inhibition of Sphase by MRE complex:
PMID:17713585
By CycE*/CDK2: G1/S transition
By CycD*/CDK2/CIp/KIP: checkpoint G1/S
d_re355( dnarepair  map ):
For role of TIM1*/TIPIN in S-phase checkpoint, replication arrest, stalled replication forks stabilisation and DNA repair during S-phase:
PMID:17102137, PMID:17116885, PMID:17296725, PMID:19793801, PMID:17582221
d_re415:( dnarepair  map ) PMID:17038621, PMID:15677884

Confidence
REF=5 FUNC=5

CDK2|​T160_pho|​Y14/15_pho:​CyclinE*@default

Identifiers
NAME:CDK2:CyclinE*

Maps_Modules
 dnarepair  map

Confidence
REF=0 FUNC=5

CDK2:​CyclinE*@default

Identifiers
NAME:CDK2:CyclinE*

Maps_Modules
 dnarepair  map

Confidence
REF=0 FUNC=5

CDK2|​Y14/15_pho:​CyclinE*@default

Identifiers
NAME:CDK2:CyclinE*

Maps_Modules
 dnarepair  map

Confidence
REF=0 FUNC=5

Modifications:
Participates in complexes:
In compartment: default
  1. CDK2:​CyclinE*@default map
  2. CDK2|​Y14/15_pho:​CyclinE*@default map
  3. (CDK2|​T160_pho:​CyclinE*)|​active@default map
  4. CDK2|​T160_pho|​Y14/15_pho:​CyclinE*@default map
Participates in reactions:
As Reactant or Product:
  1. CIP1_KIP1*@default map + CDK2:​CyclinE*@default map → map CDK2:​CIP1_KIP1*:​CyclinE*@default map
  2. CDK2:​CIP1_KIP1*:​CyclinE*@default map → map CDK2:​CyclinE*@default map + CIP1_KIP1*@default map
  3. p107*@default map + CDK2:​CyclinE*@default map → map CDK2:​CyclinE*:​p107*@default map
  4. CDK2:​CyclinE*@default map → map CDK2|​Y14/15_pho:​CyclinE*@default map
  5. CDK2|​Y14/15_pho:​CyclinE*@default map → map CDK2|​T160_pho|​Y14/15_pho:​CyclinE*@default map
  6. CyclinE*@default map + CDK2@default map → map CDK2:​CyclinE*@default map
  7. CDK2|​T160_pho|​Y14/15_pho:​CyclinE*@default map → map (CDK2|​T160_pho:​CyclinE*)|​active@default map
  8. CDK2:​CyclinE*@default map → map CyclinE*@default map + CDK2@default map
As Catalyser:
  1. G1 phase@default map → map S phase@default map
  2. E2F1:​RB1@default map → map E2F1:​RB1|​pho@default map
  3. E2F4_5*:​p107*@default map → map E2F4_5*:​p107*|​pho@default map
  4. CIP1_KIP1*@default map → map degraded
  5. ORC4*@default map + ORC5*@default map + ORC6*@default map + ORC3*@default map + ORC2*@default map + ORC1*@default map → map ORC1*:​ORC2*:​ORC3*:​ORC4*:​ORC5*:​ORC6*@default map
  6. MCM5@default map + MCM6@default map + MCM7@default map + MCM2@default map + MCM3@default map + MCM4@default map → map MCM2:​MCM3:​MCM4:​MCM5:​MCM6:​MCM7@default map
  7. ORC1*:​ORC2*:​ORC3*:​ORC4*:​ORC5*:​ORC6*@default map + MCM2:​MCM3:​MCM4:​MCM5:​MCM6:​MCM7@default map + CDT1@default map + CDC6@default map + CDC45@default map + POLA*@default map + PRIM*@default map + RPA1@Nucleus map + RPA2@Nucleus map + RPA3@Nucleus map → map CDC45:​CDC6:​CDT1:​MCM2:​MCM3:​MCM4:​MCM5:​MCM6:​MCM7:​ORC1*:​ORC2*:​ORC3*:​ORC4*:​ORC5*:​ORC6*:​POLA*:​PRIM*:​RPA1:​RPA2:​RPA3@default map
  8. FOXO*@default map → map FOXO*|​unk@default map