Gene Oxidized_ring-saturated_hydrolysed_base* map

Identifiers
BER:B-glyc:DNA:st1
DNA with oxidized or ring-saturated base or hydrolysed base
Damage caused by ROS* or X-rays
Node_Type:Generic

Maps_Modules
 dnarepair  map

References
PMID:23892398, PMID:22258607, PMID:22918414
PMID:23545420

gOxidized_ring-saturated_hydrolysed_base*@Nucleus

References
d_re527( dnarepair  map ):
For BER activation by ROS
PMID:23249296, PMID:22122466, PMID:20510258, PMID:21251944,PMID:23311711
d_re6( dnarepair  map ):
For BER:
PMID:15703371, PMID:19847258, PMID:16697054
9-1-1 complex stimulates MUTH and BER PMID:16879101
9-1-1 complex stimulates NEIL1 glycosylase and BER PMID:17395641
d_re37( dnarepair  map ):
PMID:16332722, PMID:15136767
ATR binds stalled fork and phosphorylates CHK1 that activates checkpoint, stops cell cycle
d_re177:( dnarepair  map ) reactionType:is.a

Modifications:
In compartment: Nucleus
  1. gOxidized_ring-saturated_hydrolysed_base*@Nucleus map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. gOxidized_ring-saturated_hydrolysed_base*@Nucleus map → map gDamaged_DNA*@Nucleus map
    2. gOxidized_ring-saturated_hydrolysed_base*@Nucleus map → map gC_NHEJ_DNA_st1*@Nucleus map
    3. gOxidized_ring-saturated_hydrolysed_base*@Nucleus map → map gA_NHEJ_DNA_st1*@Nucleus map
    4. gOxidized_ring-saturated_hydrolysed_base*@Nucleus map → map gHR_DNA_st1*@Nucleus map
    5. gIntact_DNA*@Nucleus map → map gOxidized_ring-saturated_hydrolysed_base*@Nucleus map
    6. gOxidized_ring-saturated_hydrolysed_base*@Nucleus map → map gSingle_strand_breaks_SSB*@Nucleus map
    7. gOxidized_ring-saturated_hydrolysed_base*@Nucleus map → map gBER_B-glyc_DNA_st2*@Nucleus map + Base@Nucleus map
    As Catalyser:
    1. ATR@default map → map ATR|​pho|​active@Nucleus map
    2. PARP1@Nucleus map → map PARP1|​PolyADPribose_unk|​pho@Nucleus map
    3. PARP2@default map → map PARP2|​unk|​pho@default map