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- Access to: Signaling network of dendritic cells in response to pathogens: a commutiy-input supported knowledgebase
Dendritic cells are antigen-presenting cells that play an essential role in linking the innate and adaptive immune systems. Much research has focused on the signaling pathways triggered upon infection of dendritic cells by various pathogens. The diagram includes detailed depictions of pathways activated downstream of different pathogen recognition receptors such as Toll-like receptors, retinoic acid-inducible gene-I-like receptors, C-type lectin receptors and nucleotide-binding oligomerization domain-like receptors.
The network comprises 249 nodes and 213 edges.
Patil S., Pincas H., Seto J., Nudelman G., Sealfon SC. Signaling network of dendritic cells in response to pathogens: a commutiy-input supported knowledgebase BMC Syst Biol 2010 4: 137. PMID