Map description

    The signalling network of EMT regulation was manually constructed in CellDesigner (, based on information extracted from 135 scientific papers after critical curation of the literature... read more


    The signalling network contains major inducers of EMT and detailed regulatory circuits that control the EMT-like program... read more

    Proliferation and Apoptosis

    Proliferative signals are represented in the network by cell cycle components such as Cyclins and cell cycle inhibitors such as p21 and p27... read more

    References...  read more

    Charion M. et al. Notch activation and p53 deletion induce EMT-like and metastasis in mouse gut cancer. Manuscript in preparation.