Complex BCL3:NFKB1_p50* map
Complex composition:

  1. BCL3 map
  2. NFKB1_p50* map


BCL3:​NFKB1_p50*@INNATE_IMMUNE_CELL_Cytosol

Identifiers
NAME:BCL3:NFKB1_p50*

Maps_Modules
MODULE:IMMUNE_STIMULATION MODULE:EFFECTOR_ACTIVATION MODULE:IMMUNOSTIMULATORY_CYTOKINE_EXPRESSION

References
 MACROPHAGE  map
CASCADE:IL10
PMID:12907458
Bcl-3‭ ‬interacted with NF-κB p50,
both Bcl-3‭ ‬and p50‭ ‬were recruited to the TNF promoter,
BCL3‭ ‬ and‭ ‬p50‭ ‬NFkB recruitment to‭ ‬TNF ‬promoter
prevents binding of‭ ‬p65/p50‭ ‬NFkB‭ ‬heterodimers
to‭ ‬TNF promotor and suppresses‭ ‬TNF ‬expression
downstream of‭ ‬IL10.


Modifications:
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. BCL3:​NFKB1_p50*@INNATE_IMMUNE_CELL_Cytosol map
Participates in reactions:
As Reactant or Product:
  1. BCL3@INNATE_IMMUNE_CELL_Cytosol map + NFKB1_p50*@INNATE_IMMUNE_CELL_Cytosol map map BCL3:​NFKB1_p50*@INNATE_IMMUNE_CELL_Cytosol map
As Catalyser:
  1. gTNF@INNATE_IMMUNE_CELL_Cytosol map map rTNF@INNATE_IMMUNE_CELL_Cytosol map