Complex CNA*:CNB*:Ca2+:Calmodulin* map
Complex composition:

  1. Calmodulin* map
  2. CNB* map
  3. Ca2+ map
  4. CNA* map

CNA*:​CNB*:​Ca2+:​Calmodulin*@INNATE_IMMUNE_CELL_Cytosol

Identifiers
NAME:CNA*:CNB*:Ca2+:Calmodulin*

Maps_Modules
MODULE:CORE_SIGNALING_PATHWAYS MODULE:IMMUNOSTIMULATORY_CORE_PATHWAYS

References
 NATURAL_KILLER  map
CASCADE:Fc_gamma_RIII
PMID:10089876, PMID:7650486, PMID:9973469
 Ca('2+) activates Calmodulin 2 ( Calmodulin )/ Protein phosphatase 3 (Calcineurin ) signal. Activated Calcineurin dephosphorylates Nuclear factor of activated T-cells cytoplasmic calcineurin-dependent 2 ( NF-AT1(NFATC2) ). 
This signaling is activated downstream of CD16 in NK cells. Additionally CD16 signaling induces NF-AT mRNA expression and protein synthesis via Calmodulin/ Calcineurin.

Modifications:
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. CNA*:​CNB*:​Ca2+:​Calmodulin*@INNATE_IMMUNE_CELL_Cytosol map
Participates in reactions:
As Reactant or Product:
  1. Ca2+:​Calmodulin*@INNATE_IMMUNE_CELL_Cytosol map + CNA*:​CNB*@INNATE_IMMUNE_CELL_Cytosol map → map CNA*:​CNB*:​Ca2+:​Calmodulin*@INNATE_IMMUNE_CELL_Cytosol map
As Catalyser:
  1. NFAT*|​pho@INNATE_IMMUNE_CELL_Cytosol map → map NFAT*@INNATE_IMMUNE_CELL_Cytosol map
  2. gNFAT*@INNATE_IMMUNE_CELL_Cytosol map → map rNFAT*@INNATE_IMMUNE_CELL_Cytosol map