Identifiers
HUGO:CALM1 HGNC:1442 ENTREZ:801 UNIPROT:P62158 GENECARDS:CALM1 HUGO:CALM2 HGNC:1445 ENTREZ:805 GENECARDS:CALM2 HUGO:CALM3 HGNC:1449 ENTREZ:808 GENECARDS:CALM3
Maps_Modules
MODULE:CORE_SIGNALING_PATHWAYS MODULE:IMMUNOSTIMULATORY_CORE_PATHWAYS
References
calmodulin 1 (phosphorylase kinase, delta)
CALML2
REACTOME:51306 KEGG:801 ATLASONC:GC_CALM1 WIKI:CALM1 REACTOME:51306 KEGG:805 WIKI:CALM2 REACTOME:51306 KEGG:808 ATLASONC:GC_CALM3 WIKI:CALM3
calmodulin 2 (phosphorylase kinase, delta)
REACTOME:51306 KEGG:805 WIKI:CALM2 REACTOME:51306 KEGG:801 ATLASONC:GC_CALM1 WIKI:CALM1 REACTOME:51306 KEGG:808 ATLASONC:GC_CALM3 WIKI:CALM3
calmodulin 3 (phosphorylase kinase, delta)
REACTOME:51306 KEGG:808 ATLASONC:GC_CALM3 WIKI:CALM3 REACTOME:51306 KEGG:801 ATLASONC:GC_CALM1 WIKI:CALM1 REACTOME:51306 KEGG:805 WIKI:CALM2
CASCADE:Fc_gamma_RIII
NATURAL_KILLER
PMID:10089876, PMID:7650486, PMID:9973469
Ca('2+) activates Calmodulin 2 ( Calmodulin )/ Protein phosphatase 3 (Calcineurin ) signal. Activated Calcineurin dephosphorylates Nuclear factor of activated T-cells cytoplasmic calcineurin-dependent 2 ( NF-AT1(NFATC2) ).
This signaling is activated downstream of CD16 in NK cells.