Protein NFAT* map

Identifiers
HUGO:NFATC1 HGNC:7775 ENTREZ:4772 UNIPROT:O95644 GENECARDS:NFATC1 HUGO:NFATC3 HGNC:7777 ENTREZ:4775 UNIPROT:Q12968 GENECARDS:NFATC3 HUGO:NFATC2 HGNC:7776 ENTREZ:4773 UNIPROT:Q13469 GENECARDS:NFATC2 HUGO:NFATC4 HGNC:7778 ENTREZ:4776 UNIPROT:Q14934 GENECARDS:NFATC4 HUGO:NFAT5 HGNC:7774 ENTREZ:10725 UNIPROT:O94916 GENECARDS:NFAT5

Maps_Modules
MODULE:CORE_SIGNALING_PATHWAYS MODULE:MIRNA_TF_IMMUNOSTIMULATORY

References
nuclear factor of activated T-cells cytoplasmic calcineurin-dependent 1
REACTOME:60119 KEGG:4772 ATLASONC:GC_NFATC1 WIKI:NFATC1
nuclear factor of activated T-cells cytoplasmic calcineurin-dependent 3
REACTOME:60123 KEGG:4775 ATLASONC:GC_NFATC3 WIKI:NFATC3
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NF-ATP, NFAT1, NFATp
REACTOME:60121 KEGG:4773 ATLASONC:NFATC2ID44004ch20q13 WIKI:NFATC2
NF-ATC, NFAT2, NFATc
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
NFAT3
KEGG:4776 ATLASONC:GC_NFATC4 WIKI:NFATC4
UNIIPROT:Q149934
nuclear factor of activated T-cells 5, tonicity-responsive
NFAT5
KEGG:10725 ATLASONC:GC_NFAT5 WIKI:NFAT5
CASCADE:Fc_gamma_RIII
 NATURAL_KILLER  map
PMID:10089876, PMID:7650486, PMID:9973469
 Ca('2+) activates Calmodulin 2 ( Calmodulin )/ Protein phosphatase 3 (Calcineurin ) signal. Activated Calcineurin dephosphorylates Nuclear factor of activated T-cells cytoplasmic calcineurin-dependent 2 ( NF-AT1(NFATC2) ). 
This signaling is activated downstream of CD16 in NK cells
PMID:7650486, PMID:9973469, PMID:9374532
NF-AT, migrates to the nucleus and activates transcription of cytokines TNF,  GM-CSF , IL-2,  IL-4. Fas ligand ( FasL ) and, possibly, IFNG.


Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. NFAT*@INNATE_IMMUNE_CELL_Cytosol map
  2. NFAT*|​pho@INNATE_IMMUNE_CELL_Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. NFAT*|​pho@INNATE_IMMUNE_CELL_Cytosol map map NFAT*@INNATE_IMMUNE_CELL_Cytosol map
    2. rNFAT*@INNATE_IMMUNE_CELL_Cytosol map map NFAT*@INNATE_IMMUNE_CELL_Cytosol map
    As Catalyser:
    1. gTNF@INNATE_IMMUNE_CELL_Cytosol map map rTNF@INNATE_IMMUNE_CELL_Cytosol map
    2. gIL2@INNATE_IMMUNE_CELL_Cytosol map map rIL2@INNATE_IMMUNE_CELL_Cytosol map
    3. gCSF2@INNATE_IMMUNE_CELL_Cytosol map map rCSF2@INNATE_IMMUNE_CELL_Cytosol map
    4. gIL4@INNATE_IMMUNE_CELL_Cytosol map map rIL4@INNATE_IMMUNE_CELL_Cytosol map
    5. gIFNG@INNATE_IMMUNE_CELL_Cytosol map map rIFNG@INNATE_IMMUNE_CELL_Cytosol map
    6. gFASL*@INNATE_IMMUNE_CELL_Cytosol map map rFASL*@INNATE_IMMUNE_CELL_Cytosol map