Complex IL10:IL10RA:IL10RB:JAK1:TYK2 map
Complex composition:

  1. IL10 map
  2. IL10RB map
  3. IL10RA map
  4. JAK1 map
  5. TYK2 map

IL10:​IL10RA|​Y446_pho|​Y496_pho:​IL10RB:​JAK1|​pho:​TYK2|​pho@INNATE_IMMUNE_CELL_Membrane

Identifiers
NAME:IL10:IL10RA:IL10RB:JAK1:TYK2

Maps_Modules
 MACROPHAGE  map
MODULE:INPUT_INHIBITORS
MODULE:IMMUNE_SUPPRESSION
MODULE:IMMUNOSUPPRESSIVE_CYTOKINE_PATHWAYS
CASCADE:IL10

References
PMID:‭21115385, PMID:7543512
‭The binding of IL-10 to its receptor activates JAK1

Modifications:
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Membrane
  1. IL10:​IL10RA|​Y446_pho|​Y496_pho:​IL10RB:​JAK1|​pho:​TYK2|​pho@INNATE_IMMUNE_CELL_Membrane map
Participates in reactions:
As Reactant or Product:
  1. IL10:​IL10RA:​IL10RB@INNATE_IMMUNE_CELL_Membrane map + JAK1|​pho@INNATE_IMMUNE_CELL_Cytosol map + TYK2|​pho@INNATE_IMMUNE_CELL_Cytosol map → map IL10:​IL10RA|​Y446_pho|​Y496_pho:​IL10RB:​JAK1|​pho:​TYK2|​pho@INNATE_IMMUNE_CELL_Membrane map
As Catalyser:
  1. STAT3@INNATE_IMMUNE_CELL_Cytosol map → map STAT3|​pho|​active@INNATE_IMMUNE_CELL_Cytosol map