Identifiers
poly (ADP-ribose) polymerase 3
HUGO:PARP3 HGNC:273 ENTREZ:10039 UNIPROT:Q9Y6F1 GENECARDS:PARP3 KEGG:10039 ATLASONC:GC_PARP3 WIKI:PARP3
Maps_Modules
dnarepair
dnarepair
References
PMID:22055391
PARP3 activated spindle checkpoint and binds to double strand breaks together with PARP1
PMID:21270334
PARPs in cellular functions (PARP3 in telomere maintenance)
PMID:22713970, PMID:21270334
PARP3 in HR and C_NHEJ
PMID:22469522, PMID:196269035
PARP3 in chromatin remodeling
PMID:22469522, PMID:22713970
APLF and PARP3 in C_NHEJ
PMID:21211721
PMID:23178593
PMID:18077224
PARP3 in C_NHEJ
PMID:22743550
References
d_re95:( dnarepair ) PMID:11955432, PMID:19772495
References
d_re216( dnarepair ):
By CDC20/APC complex:
M to G1 transition
By Mitotic checkpoint complex:
Spindle checkpoint
PARP3 activated spindle checkpoint
PMID:21270334
Tankyrase activated spindle checkpoint
PMID:23197039
d_re540( dnarepair ):
PARPs in telomere maintenance
PMID:21818122, PMID:21076181, PMID:21037379
→ Telomere maintenance@Nucleus
+ PARP1|PolyADPribose_unk|pho@Nucleus → PARP1|PolyADPribose_unk|pho:PARP3@default
→ Chromatin remodeling@Nucleus
+ LIG4:XLF*:XRCC4|hm2@default + PARP3@Nucleus + DNA-PK*|hm2|active@default + Ku80*@default + Ku70*@Nucleus + APLF@Nucleus → APLF:Artemis*|S645_pho|S385_pho|S516_pho|S518_pho:DNA-PK*|hm2:Ku70*:Ku80*:LIG4:PARP3:XLF*:XRCC4|hm2@Nucleus
+ Artemis*|S645_pho|S385_pho|S516_pho|S518_pho|active@default + Ku70*:Ku80*@Nucleus + PARP3@Nucleus → Artemis*|S645_pho|S385_pho|S516_pho|S518_pho:DNA-PK*|hm2:Ku70*:Ku80*:PARP3@Nucleus