Protein POLA*
Identifiers
polymerase (DNA directed), alpha 1, catalytic subunit
HUGO:POLA1 HGNC:9173 ENTREZ:5422 UNIPROT:P09884 GENECARDS:POLA1 REACTOME:89346 KEGG:5422 ATLASONC:GC_POLA1 WIKI:POLA1
polymerase (DNA directed), alpha 2 (70kD subunit)
HUGO:POLA2 HGNC:30073 ENTREZ:23649 UNIPROT:Q14181 GENECARDS:POLA2 REACTOME:89337 ATLASONC:GC_POLA2 WIKI:POLA2
Maps_Modules
dnarepair
References
PMID:18590585, PMID:17303408, PMID:17660363, PMID:7575488, PMID:15279786
POLA*@default
References
d_re355( dnarepair
):
For role of TIM1*/TIPIN in S-phase checkpoint, replication arrest, stalled replication forks stabilisation and DNA repair during S-phase:
PMID:17102137, PMID:17116885, PMID:17296725, PMID:19793801, PMID:17582221
Modifications:
In compartment: default
- POLA*@default
Participates in complexes:
In compartment: default
- CDC45:CDC6:CDT1:MCM2:MCM3:MCM4:MCM5:MCM6:MCM7:ORC1*:ORC2*:ORC3*:ORC4*:ORC5*:ORC6*:POLA*:PRIM*:RPA1:RPA2:RPA3@default
Participates in reactions:
As Reactant or Product:- ORC1*:ORC2*:ORC3*:ORC4*:ORC5*:ORC6*@default
+ MCM2:MCM3:MCM4:MCM5:MCM6:MCM7@default
+ CDT1@default
+ CDC6@default
+ CDC45@default
+ POLA*@default
+ PRIM*@default
+ RPA1@Nucleus
+ RPA2@Nucleus
+ RPA3@Nucleus
→
CDC45:CDC6:CDT1:MCM2:MCM3:MCM4:MCM5:MCM6:MCM7:ORC1*:ORC2*:ORC3*:ORC4*:ORC5*:ORC6*:POLA*:PRIM*:RPA1:RPA2:RPA3@default
As Catalyser:- No DNA replicarion@default
→
DNA replicarion@default