Protein TLR2
TLR2 is involved in recognition of peptidoglycan from gram-positive bacteria, bacterial lipoproteins, mycoplasma lipoprotein and mycobacterial products.It is expressed constitutively on macrophages, dendritic cells, and B cells. In some other cell types, like the epithelial cells i t can be induced .
TLR2@Cytoplasm
GeneID:7097
Modifications:
In compartment: Cytoplasm
- TLR2@Cytoplasm
Participates in complexes:
In compartment: Cytoplasm
- TLR1:TLR2@Cytoplasm
- TLR2:TLR6@Cytoplasm
- MYD88:TIRAP:TLR2@Cytoplasm
- IRAK1:MYD88:TIRAP:TLR2:TLR6@Cytoplasm
- IRAK1:IRAK4:MYD88:TIRAP:TLR1:TLR2@Cytoplasm
Participates in reactions:
As Reactant or Product:- TLR2@Cytoplasm
+ TLR1@Cytoplasm
→
TLR1:TLR2@Cytoplasm
- TLR1:TLR2@Cytoplasm
+ TIRAP@Cytoplasm
+ MYD88@Cytoplasm
→
MYD88:TIRAP:TLR2@Cytoplasm
- TLR6@Cytoplasm
+ TLR2@Cytoplasm
→
TLR2:TLR6@Cytoplasm
- IRAK1:MYD88:TIRAP:TLR2:TLR6@Cytoplasm
→
IRAK1|pho|pho|pho@Cytoplasm
- MYD88:TIRAP:TLR2@Cytoplasm
+ IRAK1@Cytoplasm
+ IRAK4@Cytoplasm
→
IRAK1:IRAK4:MYD88:TIRAP:TLR1:TLR2@Cytoplasm
- TLR2:TLR6@Cytoplasm
+ TIRAP@Cytoplasm
+ IRAK4@Cytoplasm
+ MYD88@Cytoplasm
+ IRAK1@Cytoplasm
→
IRAK1:MYD88:TIRAP:TLR2:TLR6@Cytoplasm
- Peptidoglycan@default
→
TLR2@Cytoplasm
- Lipoteichoic acid@default
→
TLR2@Cytoplasm
As Catalyser:- IRAK1:IRAK4:MYD88:TIRAP:TLR1:TLR2@Cytoplasm
→
IRAK1|pho|pho|pho@Cytoplasm