Complex IKK_alpha:IKK_beta:IKK_gamma_/NEMO:MEKK3:RIP1:TAK1:TNFR:TNF_alpha:TRADD:TRAF2/5:Ubc13:Uev1A map
Complex composition:

  1. TNF_alpha map
  2. TRADD map
  3. RIP1 map
  4. MEKK3 map
  5. TAK1 map
  6. TRAF2/5 map
  7. Ubc13 map
  8. Uev1A map
  9. TNFR map
  10. IKK_gamma_/NEMO map
  11. IKK_alpha map
  12. IKK_beta map

Modifications:
Participates in complexes:
In compartment: Cell membrane
  1. IKK_alpha:​IKK_beta:​IKK_gamma_/NEMO:​MEKK3:​RIP1|​K377_ubi:​TAK1:​TNFR|​hm3:​TNF_alpha:​TRADD:​TRAF2/5:​Ubc13:​Uev1A@Cell membrane map
  2. IKK_alpha|​pho:​IKK_beta|​pho:​IKK_gamma_/NEMO:​MEKK3:​RIP1|​K377_ubi:​TAK1:​TNFR|​hm3:​TNF_alpha:​TRADD:​TRAF2/5:​Ubc13:​Uev1A@Cell membrane map
Participates in reactions:
As Reactant or Product:
  1. IKK_alpha:​IKK_beta:​IKK_gamma_/NEMO@Cell membrane map + MEKK3:​RIP1|​K377_ubi:​TAK1:​TNFR|​hm3:​TNF_alpha:​TRADD:​TRAF2/5:​Ubc13:​Uev1A@Cell membrane map → map IKK_alpha:​IKK_beta:​IKK_gamma_/NEMO:​MEKK3:​RIP1|​K377_ubi:​TAK1:​TNFR|​hm3:​TNF_alpha:​TRADD:​TRAF2/5:​Ubc13:​Uev1A@Cell membrane map
  2. IKK_alpha:​IKK_beta:​IKK_gamma_/NEMO:​MEKK3:​RIP1|​K377_ubi:​TAK1:​TNFR|​hm3:​TNF_alpha:​TRADD:​TRAF2/5:​Ubc13:​Uev1A@Cell membrane map → map IKK_alpha|​pho:​IKK_beta|​pho:​IKK_gamma_/NEMO:​MEKK3:​RIP1|​K377_ubi:​TAK1:​TNFR|​hm3:​TNF_alpha:​TRADD:​TRAF2/5:​Ubc13:​Uev1A@Cell membrane map
  3. IKK_alpha:​IKK_beta:​IKK_gamma_/NEMO:​MEKK3:​RIP1|​K377_ubi:​TAK1:​TNFR|​hm3:​TNF_alpha:​TRADD:​TRAF2/5:​Ubc13:​Uev1A@Cell membrane map → map IKK_alpha|​pho:​IKK_beta|​pho:​IKK_gamma_/NEMO:​MEKK3:​RIP1|​K377_ubi:​TAK1:​TNFR|​hm3:​TNF_alpha:​TRADD:​TRAF2/5:​Ubc13:​Uev1A@Cell membrane map
  4. IKK_alpha|​pho:​IKK_beta|​pho:​IKK_gamma_/NEMO:​MEKK3:​RIP1|​K377_ubi:​TAK1:​TNFR|​hm3:​TNF_alpha:​TRADD:​TRAF2/5:​Ubc13:​Uev1A@Cell membrane map → map IKK_beta|​pho|​active@Cell membrane map
  5. IKK_alpha|​pho:​IKK_beta|​pho:​IKK_gamma_/NEMO:​MEKK3:​RIP1|​K377_ubi:​TAK1:​TNFR|​hm3:​TNF_alpha:​TRADD:​TRAF2/5:​Ubc13:​Uev1A@Cell membrane map → map IKK_alpha|​pho|​active@Cell membrane map
As Catalyser:
  1. IKK_alpha:​IKK_beta:​IKK_gamma_/NEMO:​MEKK3:​RIP1|​K377_ubi:​TAK1:​TNFR|​hm3:​TNF_alpha:​TRADD:​TRAF2/5:​Ubc13:​Uev1A@Cell membrane map → map IKK_alpha|​pho:​IKK_beta|​pho:​IKK_gamma_/NEMO:​MEKK3:​RIP1|​K377_ubi:​TAK1:​TNFR|​hm3:​TNF_alpha:​TRADD:​TRAF2/5:​Ubc13:​Uev1A@Cell membrane map
  2. IKK_alpha:​IKK_beta:​IKK_gamma_/NEMO:​MEKK3:​RIP1|​K377_ubi:​TAK1:​TNFR|​hm3:​TNF_alpha:​TRADD:​TRAF2/5:​Ubc13:​Uev1A@Cell membrane map → map IKK_alpha|​pho:​IKK_beta|​pho:​IKK_gamma_/NEMO:​MEKK3:​RIP1|​K377_ubi:​TAK1:​TNFR|​hm3:​TNF_alpha:​TRADD:​TRAF2/5:​Ubc13:​Uev1A@Cell membrane map
  3. I_kappa_B_alpha_:​p50 (NF_kappa_B):​p65(NF_kappa_B)@Cell membrane map → map I_kappa_B_alpha_|​S32_pho|​S36_pho:​p50 (NF_kappa_B):​p65(NF_kappa_B)@Cell membrane map