Protein Sin1.1

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Modifications:
In compartment: Cell membrane

1. Sin1.1@Cell membrane

Participates in complexes:
In compartment: Cell membrane

1. JNK:​Sin1.1@Cell membrane
2. MEKK2:​Sin1.1@Cell membrane
3. AKT|​S473_pho|​T450_pho:​Sin1.1@Cell membrane
4. Rictor:​Sin1.1:​mLST8:​mTOR@Cell membrane
5. Rictor:​Sin1.1:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane
6. Rictor:​Sin1.1:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane
7. Rictor|​T1135_pho:​Sin1.1:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane
8. PA:​Rictor:​Sin1.1:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane
9. PPR5:​Rictor:​Sin1.1:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane
10. HSP70:​Rictor:​Sin1.1:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane
11. PPR5L:​Rictor:​Sin1.1:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane
12. DEPTOR:​Rictor:​Sin1.1:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane
13. PPR5L|​pho:​Rictor:​Sin1.1:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane
14. DEPTOR|​pho:​Rictor:​Sin1.1:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane
15. 14-3-3:​Rictor|​T1135_pho:​Sin1.1:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane

In compartment: Endomembrane

1. Rictor:​Sin1.1:​TSC1:​TSC2:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Endomembrane

Participates in reactions:
As Reactant or Product:

1. Rictor:​Sin1.1:​mLST8:​mTOR@Cell membrane → Rictor:​Sin1.1:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane
2. TSC1:​TSC2@Endomembrane + Rictor:​Sin1.1:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane → Rictor:​Sin1.1:​TSC1:​TSC2:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Endomembrane
3. DEPTOR@Cell membrane + Rictor:​Sin1.1:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane → DEPTOR:​Rictor:​Sin1.1:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane
4. DEPTOR:​Rictor:​Sin1.1:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane → DEPTOR|​pho:​Rictor:​Sin1.1:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane
5. DEPTOR|​pho:​Rictor:​Sin1.1:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane → Rictor:​Sin1.1:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane + DEPTOR|​pho@Cell membrane
6. Rictor:​Sin1.1:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane + PPR5@Cell membrane → PPR5:​Rictor:​Sin1.1:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane
7. Rictor:​Sin1.1:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane + PPR5L@Cell membrane → PPR5L:​Rictor:​Sin1.1:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane
8. rSin1@Cell membrane → Sin1.1@Cell membrane
9. PPR5L:​Rictor:​Sin1.1:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane → PPR5L|​pho:​Rictor:​Sin1.1:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane
10. PPR5L|​pho:​Rictor:​Sin1.1:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane → PPR5L|​pho@Cell membrane + Rictor:​Sin1.1:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane
11. Rictor@Cell membrane + mLST8@Cell membrane → Rictor:​Sin1.1:​mLST8:​mTOR@Cell membrane
12. mTOR@Cell membrane + Sin1.1@Cell membrane → Rictor:​Sin1.1:​mLST8:​mTOR@Cell membrane
13. Sin1.1@Cell membrane + JNK@Cell membrane → JNK:​Sin1.1@Cell membrane
14. MEKK2:​Sin1.1@Cell membrane → MEKK2@Cell membrane + Sin1.1@Cell membrane
15. Sin1.1@Cell membrane + MEKK2@Cell membrane → MEKK2:​Sin1.1@Cell membrane
16. Rictor:​Sin1.1:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane + HSP70@Cell membrane → HSP70:​Rictor:​Sin1.1:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane
17. AKT|​S473_pho|​T450_pho|​active@Cell membrane + Sin1.1@Cell membrane → AKT|​S473_pho|​T450_pho:​Sin1.1@Cell membrane
18. Rictor:​Sin1.1:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane → Rictor:​Sin1.1:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane
19. Rictor:​Sin1.1:​mLST8:​mTOR@Cell membrane + PA@Cell membrane → PA:​Rictor:​Sin1.1:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane
20. PA:​Rictor:​Sin1.1:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane → PA@Cell membrane + Rictor:​Sin1.1:​mLST8:​mTOR@Cell membrane
21. Rictor:​Sin1.1:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane → Rictor|​T1135_pho:​Sin1.1:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane
22. 14-3-3@Cell membrane + Rictor|​T1135_pho:​Sin1.1:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane → 14-3-3:​Rictor|​T1135_pho:​Sin1.1:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane
23. Rictor:​Sin1.1:​mLST8:​mTOR@Cell membrane → Rictor:​Sin1.1:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane

As Catalyser:

1. AKT|​T450_pho:​PI3,4,5-P_sub_3@Cell membrane → AKT|​S473_pho|​T450_pho:​PI3,4,5-P_sub_3@Cell membrane
2. DEPTOR:​Raptor:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane → DEPTOR|​pho:​Raptor:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane
3. DEPTOR:​Rictor:​Sin1.1:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane → DEPTOR|​pho:​Rictor:​Sin1.1:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane
4. rPDGRF@Nucleus → PDGFR_beta@Cell membrane
5. gPPR5@Nucleus → rPPR5@Cell membrane
6. gSin1@Nucleus → rSin1@Cell membrane
7. PPR5:​Rictor:​Sin1.1:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane → degraded
8. PPR5:​Rictor:​Sin1.1:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane → degraded
9. PPR5L:​Rictor:​Sin1.1:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane → PPR5L|​pho:​Rictor:​Sin1.1:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane
10. AKT|​T450_pho:​PI3,4,5-P_sub_3@Cell membrane → AKT|​S473_pho|​T450_pho:​PI3,4,5-P_sub_3@Cell membrane
11. JNK@Cell membrane → JNK@Cell membrane
12. MEKK2@Cell membrane → MEKK2|​hm2@Cell membrane
13. FAK:​Paxillin:​Src@Cell membrane → FAK:​Paxillin|​Y118_pho|​Y31_pho:​Src@Cell membrane
14. Rac@Cell membrane → Rac@Cell membrane
15. PKC_alpha|​T497_pho|​T638_pho@Cell membrane → PKC_alpha|​S657_pho|​T497_pho|​T638_pho|​active@Cell membrane
16. PKC_alpha|​T497_pho@Cell membrane → PKC_alpha|​T497_pho|​T638_pho@Cell membrane
17. AKT@Cell membrane → AKT|​T450_pho@Cell membrane
18. AKT|​T450_pho@Cell membrane → AKT|​S473_pho|​T450_pho|​active@Cell membrane
19. PHLPP@Cell membrane → PHLPP@Cell membrane
20. SGK1@Cell membrane → SGK1|​S422_pho@Cell membrane