Protein CSF2RB map

Identifiers
HUGO:CSF2RB

Maps_Modules
MODULE:INPUT_ACTIVATORS
MODULE:IMMUNE_STIMULATION
MODULE:IMMUNOSTIMULATORY_CYTOKINE_PATHWAYS
 MACROPHAGE  map
CASCADE:CSF2
 DENDRITIC_CELL  map
MODULE:INPUT_INHIBITORS
MODULE:IMMUNE_SUPPRESSION
MODULE:IMMUNOSUPPRESSIVE_CYTOKINE_PATHWAYS
CASCADE:IL3

References
PMID:12393492, PMID:22323450
CSF2 acts via heterodimer receptor contains CSF2RA and SSF2RB subunits anf use JAK2 kinase
PMID:23046136
The receptor for IL-3 comprises the cytokine-specific α subunit IL3Rα and the βc subunit (CSF2RB) (

Modifications:
In compartment: INNATE_IMMUNE_CELL_Membrane
  1. CSF2RB@INNATE_IMMUNE_CELL_Membrane map
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Membrane
  1. CSF2RB:​IL3RA@INNATE_IMMUNE_CELL_Membrane map
  2. CSF2RA:​CSF2RB@INNATE_IMMUNE_CELL_Membrane map
  3. CSF2RB:​IL3:​IL3RA@INNATE_IMMUNE_CELL_Membrane map
  4. CSF2:​CSF2RA:​CSF2RB:​JAK2|​pho@INNATE_IMMUNE_CELL_Membrane map
Participates in reactions:
As Reactant or Product:
  1. CSF2RB:​IL3:​IL3RA@INNATE_IMMUNE_CELL_Membrane map → map IMMUNE_SUPRESSION@default map
  2. CSF2RA@INNATE_IMMUNE_CELL_Membrane map + CSF2RB@INNATE_IMMUNE_CELL_Membrane map → map CSF2RA:​CSF2RB@INNATE_IMMUNE_CELL_Membrane map
  3. CSF2RB@INNATE_IMMUNE_CELL_Membrane map + IL3RA@INNATE_IMMUNE_CELL_Membrane map → map CSF2RB:​IL3RA@INNATE_IMMUNE_CELL_Membrane map
  4. IL3@default map + CSF2RB:​IL3RA@INNATE_IMMUNE_CELL_Membrane map → map CSF2RB:​IL3:​IL3RA@INNATE_IMMUNE_CELL_Membrane map
  5. CSF2@default map + CSF2RA:​CSF2RB@INNATE_IMMUNE_CELL_Membrane map + JAK2@INNATE_IMMUNE_CELL_Cytosol map + JAK2@INNATE_IMMUNE_CELL_Cytosol map → map CSF2:​CSF2RA:​CSF2RB:​JAK2|​pho@INNATE_IMMUNE_CELL_Membrane map
As Catalyser:
  1. STAT1@INNATE_IMMUNE_CELL_Cytosol map → map STAT1|​pho|​active@INNATE_IMMUNE_CELL_Cytosol map
  2. STAT6@INNATE_IMMUNE_CELL_Cytosol map → map STAT6|​pho|​active@INNATE_IMMUNE_CELL_Cytosol map
  3. STAT5*@INNATE_IMMUNE_CELL_Cytosol map → map STAT5*|​pho@INNATE_IMMUNE_CELL_Cytosol map