Complex IL2RG:IL4R map
Complex composition:

  1. IL4R map
  2. IL2RG map

IL2RG:​IL4R@INNATE_IMMUNE_CELL_Membrane

Identifiers
NAME:IL2RG:IL4R

Maps_Modules
 MACROPHAGE  map
MODULE:INPUT_INHIBITORS
MODULE:IMMUNE_SUPPRESSION
MODULE:IMMUNOSUPPRESSIVE_CYTOKINE_PATHWAYS
CASCADE:

References
PMID:10358772, PMID:10856136
IL-4 mediates its effect through the
type I IL-4R, composed of the IL-4Rα and common gamma-chain (IL-2Rγ);
And, probably through type II IL-4Ris composed of the
IL-4Ra chain and IL-13Ra1

Modifications:
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Membrane
  1. IL2RG:​IL4R@INNATE_IMMUNE_CELL_Membrane map
Participates in reactions:
As Reactant or Product:
  1. IL4@default map + IL2RG:​IL4R@INNATE_IMMUNE_CELL_Membrane map → map IL2RG:​IL4:​IL4R@INNATE_IMMUNE_CELL_Membrane map
  2. IL2RG@INNATE_IMMUNE_CELL_Membrane map + IL4R@INNATE_IMMUNE_CELL_Membrane map → map IL2RG:​IL4R@INNATE_IMMUNE_CELL_Membrane map
  3. IL2RG@INNATE_IMMUNE_CELL_Membrane map + IL4R@INNATE_IMMUNE_CELL_Membrane map → map IL2RG:​IL4R@INNATE_IMMUNE_CELL_Membrane map
  4. IL4@default map + IL2RG:​IL4R@INNATE_IMMUNE_CELL_Membrane map + JAK3@INNATE_IMMUNE_CELL_Cytosol map + JAK1@INNATE_IMMUNE_CELL_Cytosol map + JAK2@INNATE_IMMUNE_CELL_Cytosol map → map IL2RG:​IL4:​IL4R:​JAK1|​pho:​JAK2:​JAK3@INNATE_IMMUNE_CELL_Membrane map
As Catalyser: