Protein _beta_TRCP* map

Identifiers
beta-transducin repeat containing
HUGO:BTRC HGNC:1144 ENTREZ:8945 UNIPROT:Q9Y297 GENECARDS:BTRC REACTOME:55056 KEGG:8945 ATLASONC:BTRCID451ch10q24 WIKI:BTRC

Maps_Modules
 apoptosis  map
 apoptosis  map
 apoptosis  map
 dnarepair  map
 dnarepair  map
 dnarepair  map
 survival  map
 survival  map
 survival  map

References
FANCM is phosphorylated by PLK1 and ubiquitinated by beta-TRCP (in the SCF complex) in response to G2/M checkpoint.
Phosphorylated FANCM is degraded and FANCONI pathway is inhibited during mitosis.
PMID:19270156, PMID:19686080
For checkpoint
PMID:15459660

Modifications:
In compartment: default
  1. _beta_TRCP*@default map
Participates in complexes:
In compartment: default
  1. CUL1:​RBX1:​SKP1:​SKP2:​_beta_TRCP*@default map
Participates in reactions:
As Reactant or Product:
  1. _beta_TRCP*@default map + SKP1@default map + CUL1@default map + RBX1@default map + SKP2@default map → map CUL1:​RBX1:​SKP1:​SKP2:​_beta_TRCP*@default map
As Catalyser:
  1. FANCM|​pho@default map → map degraded
  2. CyclinD*@default map → map degraded
  3. CyclinE*@default map → map degraded
  4. CDC25A@default map → map degraded
  5. CDC25B@default map → map degraded
  6. WEE1|​pho@default map → map degraded
  7. EMI1*|​pho@default map → map degraded