Protein CHEK2 map

Identifiers
CHK2 checkpoint homolog (S. pombe)
HUGO:CHEK2 HGNC:16627 ENTREZ:11200 UNIPROT:O96017 GENECARDS:CHEK2 REACTOME:87288 KEGG:11200 ATLASONC:CHEK2ID312 WIKI:CHEK2
Q9UGF0

Maps_Modules
 dnarepair  map
 dnarepair  map
 dnarepair  map
 cellcycle  map
 cellcycle  map
 cellcycle  map

References
PMID:15459660, PMID:15810020, PMID:18566216, PMID:17464182

CHEK2|​pho|​active@default

References
d_re34:( dnarepair  map ) PMID:19788416
d_re65( dnarepair  map ):
Phosphorylation of CDC25A, B or C by CHEK1 and CHEK2 inactivates CDC25, prevents activating de-phosphorylation of CDKs by CDC25 A, B, C
and stops cell cycle propagation
kegg cell cycle
PMID:20126263, PMID:17568790
d_re70:( dnarepair  map ) PMID:18971944
d_re71( dnarepair  map ):
For inactivation of EXO1 by 53BP1-mediated phosphorylation:
PMID:18756267, PMID:15867354
ATM and ATR phosphorylate EXO1 and lead to EXO1 ubiquitination and degradation:
PMID:18048416, PMID:11438669, PMID:20019063
d_re188( dnarepair  map ):
PMID:18931676, PMID:19686080, PMID:17296736
Link between cell cycle and activation of Fanconi pathway

Modifications:
In compartment: default
  1. CHEK2@default map
  2. CHEK2|​pho|​active@default map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. CHEK2@default map → map CHEK2|​pho|​active@default map
    As Catalyser:
    1. FANCE@default map → map FANCE|​S376_pho|​T346_pho@default map
    2. CDC25C@default map → map CDC25C|​S216_pho@default map
    3. p53*@default map → map p53*|​pho|​ace|​active@default map
    4. BRCA1@default map → map BRCA1|​S988_pho|​S1387_pho|​S1423_pho|​S1497_pho|​S1524_pho|​active@default map
    5. CDC25A@default map → map CDC25A|​S76_pho|​S178_pho|​S124_pho|​S279_pho|​S293_pho@default map
    6. CDC25B@default map → map CDC25B|​S230_pho|​S151_pho|​S323_pho@default map
    7. XRCC1@default map → map XRCC1|​pho@default map
    8. EXO1@default map → map EXO1|​S692_pho|​S372_pho|​S567_pho|​S587_pho@default map