Complex BARD1:BRCA1:BRCA2:BRIT1*:DSS1*:FANCD2:FANCN*:RAD51:RAD52:SFPQ:XRCC2:XRCC3
Complex composition:
- RAD52
- FANCN*
- FANCD2
- XRCC2
- XRCC3
- RAD51
- DSS1*
- BRCA2
- BRCA1
- BARD1
- BRIT1*
- SFPQ
BARD1:BRCA1:BRCA2:BRIT1*:DSS1*:FANCD2|K561_ubi|pho:FANCN*:RAD51:RAD52:SFPQ:XRCC2:XRCC3@default
Identifiers
NAME:BARD1:BRCA1:BRCA2:BRIT1*:DSS1*:FANCD2:FANCN*:RAD51:RAD52:SFPQ:XRCC2:XRCC3
Maps_Modules
dnarepair
References
d_re146( dnarepair
):
Link between Fanconi and HR:
PMID:15650050, PMID:19686080
d_re136( dnarepair
):
Regulation of HR DNA repair foci formation regulation by UBc13:
PMID:17349954
For role of SMARCAL1/RPA in stalled relication fork repair and in the homologous recombination:
PMID:19841479, PMID:19793861, PMID:19793862
MCM8*/MCM9* colocolize at RAD51 filament and reqired for interstrand crosslinks repair
PMID:22771115
Confidence
REF=5 FUNC=4
Modifications:
Participates in complexes:
In compartment: default
- BARD1:BRCA1:BRCA2:BRIT1*:DSS1*:FANCD2|K561_ubi|pho:FANCN*:RAD51:RAD52:SFPQ:XRCC2:XRCC3@default
Participates in reactions:
As Reactant or Product:- RAD51:XRCC2:XRCC3@default
+ BARD1:BRCA1@default
+ RAD52@default
+ BRCA2:DSS1*@default
+ FANCN*@default
+ FANCD2|K561_ubi|pho@default
+ BRIT1*@default
+ SFPQ@default
→
BARD1:BRCA1:BRCA2:BRIT1*:DSS1*:FANCD2|K561_ubi|pho:FANCN*:RAD51:RAD52:SFPQ:XRCC2:XRCC3@default
As Catalyser:- gHR_DNA_st2*@Nucleus
→
gHR_DNA_st3*@Nucleus