Identifiers
RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae), RAD51A
HUGO:RAD51 HGNC:9817 ENTREZ:5888 UNIPROT:Q06609 GENECARDS:RAD51 REACTOME:62638 KEGG:5888 ATLASONC:GC_RAD51 WIKI:RAD51
RAD51-like 1 (S. cerevisiae), RAD51B
HUGO:RAD51L1 GENECARDS:RAD51L1 KEGG:5890 WIKI:RAD51L1
RAD51 homolog C (S. cerevisiae)
HUGO:RAD51C HGNC:9820 ENTREZ:5889 UNIPROT:O43502 GENECARDS:RAD51C REACTOME:217113 KEGG:5889 ATLASONC:GC_RAD51C WIKI:RAD51C
RAD51-like 3 (S. cerevisiae), RAD51D
HUGO:RAD51L3 GENECARDS:RAD51L3 KEGG:5892 WIKI:RAD51L3
Maps_Modules
dnarepair
dnarepair
References
PMID:19772495, PMID:16697054, PMID:19847258
References
d_re166( dnarepair ):
Fanconi recognition complex as FA core complex recruits NER, HR, TLS proteins that collectively repair the ICL. If Fanconi proteins participating in the recognition are dysactivated, there is no any other mechanism to recognize ILSs, therefore, even if NER, HR and TLS are correct, they will not perform the repair without core Fanconi proteins.
PMID:19686080
+ XRCC2@default + RAD51@default → RAD51:XRCC2:XRCC3@default
+ BARD1:BRCA1@default + RAD52@default + BRCA2:DSS1*@default + FANCN*@default + FANCD2|K561_ubi|pho@default + BRIT1*@default + SFPQ@default → BARD1:BRCA1:BRCA2:BRIT1*:DSS1*:FANCD2|K561_ubi|pho:FANCN*:RAD51:RAD52:SFPQ:XRCC2:XRCC3@default
+ BRCA1|S988_pho|S1387_pho|S1423_pho|S1497_pho|S1524_pho|active@default + BRCA2@default + NBS1*|S343_pho@default + RAD51@default + PCNA@default + H2AFX|S139_pho|ubi@default + TIP60*@default → BRCA1:BRCA2:FANCD2|K561_ubi|pho:FANCI|K523_ubi|pho:H2AFX|S139_pho|ubi:NBS1*|S343_pho:PCNA:RAD51:TIP60*@default
→ BRCA1:BRCA2:FANCD2|pho:FANCI|pho:H2AFX|S139_pho|ubi:NBS1*|S343_pho:PCNA:RAD51:TIP60*@default