Protein S6K1

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Modifications:
In compartment: Cell membrane

1. S6K1|​ubi@Cell membrane
2. S6K1|​S17_pho@Cell membrane
3. S6K1|​S371_pho|​S411_pho|​S418_pho|​T421_pho|​S424_pho|​S17_pho@Cell membrane
4. S6K1|​T389_pho|​S371_pho|​S411_pho|​S418_pho|​T421_pho|​S424_pho|​S17_pho|​active@Cell membrane
5. S6K1|​T229_pho|​T389_pho|​S371_pho|​S411_pho|​S418_pho|​T421_pho|​S424_pho|​S17_pho|​active@Cell membrane

In compartment: Mitochondria

1. S6K1|​T229_pho|​S371_pho|​S411_pho|​S418_pho|​T421_pho|​S424_pho|​S17_pho@Mitochondria
2. S6K1|​T229_pho|​T389_pho|​S371_pho|​S411_pho|​S418_pho|​T421_pho|​S424_pho|​S17_pho|​active@Mitochondria

In compartment: Nucleus

1. S6K1@Nucleus
2. S6K1|​S17_pho@Nucleus

Participates in complexes:
In compartment: Cell membrane

1. S6K1|​S371_pho|​S411_pho|​S418_pho|​T421_pho|​S424_pho|​S17_pho:​eIF3@Cell membrane
2. S6K1|​T229_pho|​T389_pho|​S371_pho|​S411_pho|​S418_pho|​T421_pho|​S424_pho|​S17_pho:​SKAR@Cell membrane
3. S6K1|​T229_pho|​T389_pho|​S371_pho|​S411_pho|​S418_pho|​T421_pho|​S424_pho|​S17_pho:​SKAR|​S383_pho|​S385_pho@Cell membrane
4. 4EBP-1:​S6K1|​S371_pho|​S411_pho|​S418_pho|​T421_pho|​S424_pho|​S17_pho:​eIF3:​eIF4E:​m7GTP:​mRNA@Cell membrane
5. CBC:​EJC:​S6K1|​T229_pho|​T389_pho|​S371_pho|​S411_pho|​S418_pho|​T421_pho|​S424_pho|​S17_pho:​SKAR|​S383_pho|​S385_pho:​m7GTP:​mRNA@Cell membrane
6. 4EBP-1|​T37_pho|​T46_pho|​S65_pho|​S70_pho:​Raptor|​S722_pho|​S719_pho|​S721_pho:​S6K1|​T389_pho|​S371_pho|​S411_pho|​S418_pho|​T421_pho|​S424_pho|​S17_pho:​eIF3:​eIF4E:​mRNA:​mTOR|​S2481_pho|​S1261_pho@Cell membrane
7. 4EBP-1:​Raptor|​S722_pho|​S719_pho|​S721_pho|​S863_pho:​S6K1|​S371_pho|​S411_pho|​S418_pho|​T421_pho|​S424_pho|​S17_pho:​eIF3:​eIF4E:​m7GTP:​mRNA:​mTOR|​S2481_pho|​S1261_pho@Cell membrane

In compartment: Nucleus

1. CK2:​S6K1@Nucleus
2. CK2:​S6K1|​S17_pho@Nucleus

Participates in reactions:
As Reactant or Product:

1. S6K1|​S371_pho|​S411_pho|​S418_pho|​T421_pho|​S424_pho|​S17_pho@Cell membrane → S6K1|​T389_pho|​S371_pho|​S411_pho|​S418_pho|​T421_pho|​S424_pho|​S17_pho|​active@Cell membrane
2. S6K1|​S17_pho@Cell membrane → S6K1|​S371_pho|​S411_pho|​S418_pho|​T421_pho|​S424_pho|​S17_pho@Cell membrane
3. S6K1|​T389_pho|​S371_pho|​S411_pho|​S418_pho|​T421_pho|​S424_pho|​S17_pho|​active@Cell membrane → S6K1|​T229_pho|​T389_pho|​S371_pho|​S411_pho|​S418_pho|​T421_pho|​S424_pho|​S17_pho|​active@Cell membrane
4. PDGF:​PDGFR_beta@Cell membrane → S6K1|​T389_pho|​S371_pho|​S411_pho|​S418_pho|​T421_pho|​S424_pho|​S17_pho|​active@Cell membrane
5. S6K1|​S371_pho|​S411_pho|​S418_pho|​T421_pho|​S424_pho|​S17_pho@Cell membrane → S6K1|​T389_pho|​S371_pho|​S411_pho|​S418_pho|​T421_pho|​S424_pho|​S17_pho|​active@Cell membrane
6. S6K1|​S371_pho|​S411_pho|​S418_pho|​T421_pho|​S424_pho|​S17_pho@Cell membrane → S6K1|​T389_pho|​S371_pho|​S411_pho|​S418_pho|​T421_pho|​S424_pho|​S17_pho|​active@Cell membrane
7. S6K1|​S371_pho|​S411_pho|​S418_pho|​T421_pho|​S424_pho|​S17_pho@Cell membrane + eIF3@Cell membrane → S6K1|​S371_pho|​S411_pho|​S418_pho|​T421_pho|​S424_pho|​S17_pho:​eIF3@Cell membrane
8. S6K1|​S371_pho|​S411_pho|​S418_pho|​T421_pho|​S424_pho|​S17_pho:​eIF3@Cell membrane + 4EBP-1:​eIF4E:​m7GTP:​mRNA@Cell membrane → 4EBP-1:​S6K1|​S371_pho|​S411_pho|​S418_pho|​T421_pho|​S424_pho|​S17_pho:​eIF3:​eIF4E:​m7GTP:​mRNA@Cell membrane
9. FKBP38:​GTP:​Raptor|​S722_pho|​S719_pho|​S721_pho|​S863_pho:​Rheb:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane + 4EBP-1:​S6K1|​S371_pho|​S411_pho|​S418_pho|​T421_pho|​S424_pho|​S17_pho:​eIF3:​eIF4E:​m7GTP:​mRNA@Cell membrane → 4EBP-1:​Raptor|​S722_pho|​S719_pho|​S721_pho|​S863_pho:​S6K1|​S371_pho|​S411_pho|​S418_pho|​T421_pho|​S424_pho|​S17_pho:​eIF3:​eIF4E:​m7GTP:​mRNA:​mTOR|​S2481_pho|​S1261_pho@Cell membrane
10. 4EBP-1:​Raptor|​S722_pho|​S719_pho|​S721_pho|​S863_pho:​S6K1|​S371_pho|​S411_pho|​S418_pho|​T421_pho|​S424_pho|​S17_pho:​eIF3:​eIF4E:​m7GTP:​mRNA:​mTOR|​S2481_pho|​S1261_pho@Cell membrane → 4EBP-1|​T37_pho|​T46_pho|​S65_pho|​S70_pho:​Raptor|​S722_pho|​S719_pho|​S721_pho:​S6K1|​T389_pho|​S371_pho|​S411_pho|​S418_pho|​T421_pho|​S424_pho|​S17_pho:​eIF3:​eIF4E:​mRNA:​mTOR|​S2481_pho|​S1261_pho@Cell membrane
11. 4EBP-1|​T37_pho|​T46_pho|​S65_pho|​S70_pho:​Raptor|​S722_pho|​S719_pho|​S721_pho:​S6K1|​T389_pho|​S371_pho|​S411_pho|​S418_pho|​T421_pho|​S424_pho|​S17_pho:​eIF3:​eIF4E:​mRNA:​mTOR|​S2481_pho|​S1261_pho@Cell membrane → Raptor|​S722_pho|​S719_pho|​S721_pho:​eIF3:​eIF4E:​m7GTP:​mRNA:​mTOR|​S2481_pho|​S1261_pho@Cell membrane + 4EBP-1|​T37_pho|​T46_pho|​S65_pho|​S70_pho@Cell membrane
12. 4EBP-1|​T37_pho|​T46_pho|​S65_pho|​S70_pho:​Raptor|​S722_pho|​S719_pho|​S721_pho:​S6K1|​T389_pho|​S371_pho|​S411_pho|​S418_pho|​T421_pho|​S424_pho|​S17_pho:​eIF3:​eIF4E:​mRNA:​mTOR|​S2481_pho|​S1261_pho@Cell membrane → Raptor|​S722_pho|​S719_pho|​S721_pho:​eIF3:​eIF4E:​m7GTP:​mRNA:​mTOR|​S2481_pho|​S1261_pho@Cell membrane + S6K1|​T389_pho|​S371_pho|​S411_pho|​S418_pho|​T421_pho|​S424_pho|​S17_pho|​active@Cell membrane
13. 4EBP-1:​Raptor|​S722_pho|​S719_pho|​S721_pho|​S863_pho:​S6K1|​S371_pho|​S411_pho|​S418_pho|​T421_pho|​S424_pho|​S17_pho:​eIF3:​eIF4E:​m7GTP:​mRNA:​mTOR|​S2481_pho|​S1261_pho@Cell membrane → 4EBP-1|​T37_pho|​T46_pho|​S65_pho|​S70_pho:​Raptor|​S722_pho|​S719_pho|​S721_pho:​S6K1|​T389_pho|​S371_pho|​S411_pho|​S418_pho|​T421_pho|​S424_pho|​S17_pho:​eIF3:​eIF4E:​mRNA:​mTOR|​S2481_pho|​S1261_pho@Cell membrane
14. S6K1|​S371_pho|​S411_pho|​S418_pho|​T421_pho|​S424_pho|​S17_pho@Cell membrane → S6K1|​T389_pho|​S371_pho|​S411_pho|​S418_pho|​T421_pho|​S424_pho|​S17_pho|​active@Cell membrane
15. S6K1|​T229_pho|​T389_pho|​S371_pho|​S411_pho|​S418_pho|​T421_pho|​S424_pho|​S17_pho:​SKAR@Cell membrane → S6K1|​T229_pho|​T389_pho|​S371_pho|​S411_pho|​S418_pho|​T421_pho|​S424_pho|​S17_pho:​SKAR|​S383_pho|​S385_pho@Cell membrane
16. SKAR@Cell membrane + S6K1|​T229_pho|​T389_pho|​S371_pho|​S411_pho|​S418_pho|​T421_pho|​S424_pho|​S17_pho|​active@Cell membrane → S6K1|​T229_pho|​T389_pho|​S371_pho|​S411_pho|​S418_pho|​T421_pho|​S424_pho|​S17_pho:​SKAR@Cell membrane
17. CBC:​EJC:​m7GTP:​mRNA@Cell membrane + S6K1|​T229_pho|​T389_pho|​S371_pho|​S411_pho|​S418_pho|​T421_pho|​S424_pho|​S17_pho:​SKAR|​S383_pho|​S385_pho@Cell membrane → CBC:​EJC:​S6K1|​T229_pho|​T389_pho|​S371_pho|​S411_pho|​S418_pho|​T421_pho|​S424_pho|​S17_pho:​SKAR|​S383_pho|​S385_pho:​m7GTP:​mRNA@Cell membrane
18. CBC:​EJC:​S6K1|​T229_pho|​T389_pho|​S371_pho|​S411_pho|​S418_pho|​T421_pho|​S424_pho|​S17_pho:​SKAR|​S383_pho|​S385_pho:​m7GTP:​mRNA@Cell membrane → mRNA translation@Cell membrane
19. S6K1|​S17_pho@Cell membrane → S6K1|​ubi@Cell membrane
20. S6K1@Nucleus + CK2@Nucleus → CK2:​S6K1@Nucleus
21. CK2:​S6K1@Nucleus → CK2:​S6K1|​S17_pho@Nucleus
22. CK2:​S6K1|​S17_pho@Nucleus → CK2@Nucleus + S6K1|​S17_pho@Nucleus
23. S6K1|​S17_pho@Nucleus → S6K1|​S17_pho@Cell membrane
24. S6K1|​T229_pho|​T389_pho|​S371_pho|​S411_pho|​S418_pho|​T421_pho|​S424_pho|​S17_pho|​active@Mitochondria → S6K1|​T229_pho|​S371_pho|​S411_pho|​S418_pho|​T421_pho|​S424_pho|​S17_pho@Mitochondria
25. S6K1|​T229_pho|​T389_pho|​S371_pho|​S411_pho|​S418_pho|​T421_pho|​S424_pho|​S17_pho|​active@Cell membrane → S6K1|​T229_pho|​T389_pho|​S371_pho|​S411_pho|​S418_pho|​T421_pho|​S424_pho|​S17_pho|​active@Mitochondria
26. S6K1|​T229_pho|​S371_pho|​S411_pho|​S418_pho|​T421_pho|​S424_pho|​S17_pho@Mitochondria → Apoptosis@Mitochondria
27. PDGF:​PDGFR_beta@Cell membrane → S6K1|​T389_pho|​S371_pho|​S411_pho|​S418_pho|​T421_pho|​S424_pho|​S17_pho|​active@Cell membrane

As Catalyser:

1. eIF4B@Cell membrane → eIF4B|​S422_pho@Cell membrane
2. eEF2K|​S500_pho|​active@Cell membrane → eEF2K|​S366_pho|​S500_pho@Cell membrane
3. PDCD4@Cell membrane → PDCD4|​S67_pho@Cell membrane
4. 4EBP-1:​Raptor|​S722_pho|​S719_pho|​S721_pho|​S863_pho:​S6K1|​S371_pho|​S411_pho|​S418_pho|​T421_pho|​S424_pho|​S17_pho:​eIF3:​eIF4E:​m7GTP:​mRNA:​mTOR|​S2481_pho|​S1261_pho@Cell membrane → 4EBP-1|​T37_pho|​T46_pho|​S65_pho|​S70_pho:​Raptor|​S722_pho|​S719_pho|​S721_pho:​S6K1|​T389_pho|​S371_pho|​S411_pho|​S418_pho|​T421_pho|​S424_pho|​S17_pho:​eIF3:​eIF4E:​mRNA:​mTOR|​S2481_pho|​S1261_pho@Cell membrane
5. 4EBP-1:​Raptor|​S722_pho|​S719_pho|​S721_pho|​S863_pho:​S6K1|​S371_pho|​S411_pho|​S418_pho|​T421_pho|​S424_pho|​S17_pho:​eIF3:​eIF4E:​m7GTP:​mRNA:​mTOR|​S2481_pho|​S1261_pho@Cell membrane → 4EBP-1|​T37_pho|​T46_pho|​S65_pho|​S70_pho:​Raptor|​S722_pho|​S719_pho|​S721_pho:​S6K1|​T389_pho|​S371_pho|​S411_pho|​S418_pho|​T421_pho|​S424_pho|​S17_pho:​eIF3:​eIF4E:​mRNA:​mTOR|​S2481_pho|​S1261_pho@Cell membrane
6. rpS6/40S subunit@Cell membrane → rpS6/40S subunit|​S235_pho|​S236_pho|​S240_pho|​S244_pho|​S247_pho@Cell membrane
7. S6K1|​T229_pho|​T389_pho|​S371_pho|​S411_pho|​S418_pho|​T421_pho|​S424_pho|​S17_pho:​SKAR@Cell membrane → S6K1|​T229_pho|​T389_pho|​S371_pho|​S411_pho|​S418_pho|​T421_pho|​S424_pho|​S17_pho:​SKAR|​S383_pho|​S385_pho@Cell membrane
8. GSK3alpha/beta@Cell membrane → GSK3alpha/beta|​S21/9_pho@Cell membrane
9. UBF|​ace|​S484_pho|​S388_pho|​hm2@Nucleus → UBF|​pho|​ace|​S484_pho|​S388_pho|​hm2@Nucleus
10. CK2:​S6K1@Nucleus → CK2:​S6K1|​S17_pho@Nucleus
11. PP1_gamma_:​URI@Mitochondria → PP1_gamma_:​URI|​S371_pho@Mitochondria
12. BAD@Mitochondria → BAD|​S136_pho@Mitochondria
13. IRS-1|​pho@Cell membrane → IRS-1|​S639_pho|​S309_pho|​pho|​S636_pho@Cell membrane
14. mTOR@Cell membrane → mTOR|​S2448_pho|​T2446_pho@Cell membrane
15. CCT_alpha:​CCT_beta:​CCT_delta:​CCT_epsilon:​CCT_eta:​CCT_gamma:​CCT_theta:​CCT_zeta@Cell membrane → CCT_alpha:​CCT_beta|​S260_pho:​CCT_delta:​CCT_epsilon:​CCT_eta:​CCT_gamma:​CCT_theta:​CCT_zeta@Cell membrane
16. gIRS-1@Nucleus → rIRS-1@Cell membrane
17. Rictor:​Sin1.1:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane → Rictor|​T1135_pho:​Sin1.1:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane