Simple molecule cGAMP map
cGAMP@INNATE_IMMUNE_CELL_Cytosol

Maps_Modules
MODULE:INPUT_ACTIVATORS MODULE:TUMOR_RECOGNTITON MODULE:DANGER_SIGNAL_PATHWAYS

References
 DENDRITIC_CELL  map
CASCADE:STING
cyclic-GMP-AMP
PMID:24766893
Cytosolic DNA activates cGAS to form a dimeric cGAS-DNA complex which synthesizes 2′3′-cGAMP from ATP and GTP.

Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. cGAMP@INNATE_IMMUNE_CELL_Cytosol map
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. STING*:​cGAMP@INNATE_IMMUNE_CELL_Cytosol map
  2. STING*:​TBK1:​cGAMP@INNATE_IMMUNE_CELL_Cytosol map
Participates in reactions:
As Reactant or Product:
  1. ATP@INNATE_IMMUNE_CELL_Cytosol map → map cGAMP@INNATE_IMMUNE_CELL_Cytosol map
  2. STING*@INNATE_IMMUNE_CELL_Cytosol map + cGAMP@INNATE_IMMUNE_CELL_Cytosol map → map STING*:​cGAMP@INNATE_IMMUNE_CELL_Cytosol map
  3. STING*:​cGAMP@INNATE_IMMUNE_CELL_Cytosol map + TBK1@INNATE_IMMUNE_CELL_Cytosol map → map STING*:​TBK1:​cGAMP@INNATE_IMMUNE_CELL_Cytosol map
As Catalyser:
  1. IRF3@INNATE_IMMUNE_CELL_Cytosol map → map IRF3|​pho@INNATE_IMMUNE_CELL_Cytosol map
  2. IKBKG:​IKK_alpha_*:​IKK_beta_*@INNATE_IMMUNE_CELL_Cytosol map → map IKBKG|​ubi:​IKK_beta_*|​pho:​MHC_class_I*@INNATE_IMMUNE_CELL_Cytosol map