Protein TIM1*
Identifiers
timeless homolog (Drosophila)
HUGO:TIMELESS HGNC:11813 ENTREZ:8914 UNIPROT:Q9UNS1 GENECARDS:TIMELESS KEGG:8914 ATLASONC:GC_TIMELESS WIKI:TIMELESS
Maps_Modules
dnarepair
dnarepair
References
PMID:17102137, PMID:17116885, PMID:12875843, PMID:17296725, PMID:15798197
Role of TIM/TIPIN complex in DNA replication
PMID:17141802, PMID:12875843
For S-phase checkpoint
PMID:15459660,PMID:17102137, PMID:17116885, PMID:17296725, PMID:19793801, PMID:17582221, PMID:18677104
Modifications:
In compartment: default
- TIM1*@default
Participates in complexes:
In compartment: default
- TIM1*:TIPIN@default
- ATRIP:ATR|pho:CHEK1|pho:CLSPN|pho:PCNA|K164_ubi:TIM1*@default
- ATRIP:ATR|pho:CHEK1|pho:CLSPN|pho:RPA1:RPA2:RPA3:TIM1*:TIPIN@default
Participates in reactions:
As Reactant or Product:- TIM1*@default
+ CLSPN|pho@default
+ PCNA|K164_ubi@default
+ ATRIP:ATR|pho@default
+ CHEK1|pho|active@Nucleus
→
ATRIP:ATR|pho:CHEK1|pho:CLSPN|pho:PCNA|K164_ubi:TIM1*@default
- TIPIN@default
+ TIM1*@default
→
TIM1*:TIPIN@default
- ATRIP:ATR|pho:CLSPN|pho:RPA1:RPA2:RPA3@default
+ TIPIN@default
+ TIM1*@default
+ CHEK1|pho|active@default
→
ATRIP:ATR|pho:CHEK1|pho:CLSPN|pho:RPA1:RPA2:RPA3:TIM1*:TIPIN@default
As Catalyser:- S phase@default
→
G2 phase@default
- gDamaged_DNA*@Nucleus
→
gRepaired_DNA*@Nucleus
- ORC1*:ORC2*:ORC3*:ORC4*:ORC5*:ORC6*@default
+ MCM2:MCM3:MCM4:MCM5:MCM6:MCM7@default
+ CDT1@default
+ CDC6@default
+ CDC45@default
+ POLA*@default
+ PRIM*@default
+ RPA1@Nucleus
+ RPA2@Nucleus
+ RPA3@Nucleus
→
CDC45:CDC6:CDT1:MCM2:MCM3:MCM4:MCM5:MCM6:MCM7:ORC1*:ORC2*:ORC3*:ORC4*:ORC5*:ORC6*:POLA*:PRIM*:RPA1:RPA2:RPA3@default
- No DNA replicarion@default
→
DNA replicarion@default