Protein FANCF
Identifiers
Fanconi anemia, complementation group F
HUGO:FANCF HGNC:3587 ENTREZ:2188 UNIPROT:Q9NPI8 GENECARDS:FANCF REACTOME:54636 KEGG:2188 ATLASONC:FANCFID294 WIKI:FANCF
Maps_Modules
dnarepair
dnarepair
References
PMID:19686080, PMID:19622404, PMID:18931676
FA core complex regulates REV1 and activated TLS
PMID:22266823
Modifications:
In compartment: default
- FANCF@default
Participates in complexes:
In compartment: default
- FANCC:FANCE|S376_pho|T346_pho:FANCF@default
- BLM:FAAP100*:FAAP20*:FAAP24*:FANCA|pho:FANCB:FANCC:FANCE|S376_pho|T346_pho:FANCF:FANCG|S7_pho:FANCL:FANCM:HES1@default
- BLM:FAAP100*:FAAP20*:FAAP24*:FANCA|pho:FANCB:FANCC:FANCE|S376_pho|T346_pho:FANCF:FANCG|S7_pho:FANCL:FANCM:HES1:RPA1:RPA2:RPA3:TOP3A@default
Participates in reactions:
As Reactant or Product:- FANCC@default
+ FANCE|S376_pho|T346_pho@default
+ FANCF@default
→
FANCC:FANCE|S376_pho|T346_pho:FANCF@default
- FANCA|pho:FANCG|S7_pho@default
+ FANCC:FANCE|S376_pho|T346_pho:FANCF@default
+ FAAP24*:FANCM@default
+ FAAP100*:FANCB:FANCL@default
+ BLM@Nucleus
+ HES1@default
+ FAAP20*@default
→
BLM:FAAP100*:FAAP20*:FAAP24*:FANCA|pho:FANCB:FANCC:FANCE|S376_pho|T346_pho:FANCF:FANCG|S7_pho:FANCL:FANCM:HES1@default
- BLM:FAAP100*:FAAP20*:FAAP24*:FANCA|pho:FANCB:FANCC:FANCE|S376_pho|T346_pho:FANCF:FANCG|S7_pho:FANCL:FANCM:HES1@default
+ TOP3A@default
+ RPA1:RPA2:RPA3@default
→
BLM:FAAP100*:FAAP20*:FAAP24*:FANCA|pho:FANCB:FANCC:FANCE|S376_pho|T346_pho:FANCF:FANCG|S7_pho:FANCL:FANCM:HES1:RPA1:RPA2:RPA3:TOP3A@default
As Catalyser:- gFanconi_DNA_st2*@Nucleus
→
gFanconi_DNA_st3*@Nucleus
- FANCD2|pho@default
→
FANCD2|K561_ubi|pho@default
- FANCI|pho@default
→
FANCI|K523_ubi|pho@default
- gFanconi_DNA_st4*@Nucleus
→
gFanconi_DNA_st5*@Nucleus
- FANCD2@default
→
FANCD2|pho@default
- FANCD2|K561_ubi|pho@default
+ MRE11*:NBS1*|S343_pho:RAD50@default
+ ATR|pho|active@Nucleus
→
ATR|pho:FANCD2|K561_ubi|pho:MRE11*:NBS1*|S343_pho:RAD50@default
- gTLS_DNA_st1*@Nucleus
→
gTLS_DNA_st2*@Nucleus