Protein TGFBR1 map

Identifiers
HUGO:TGFBR1

Maps_Modules
 MACROPHAGE  map
MODULE:INPUT_INHIBITORS
MODULE:IMMUNE_SUPPRESSION
MODULE:IMMUNOSUPPRESSIVE_CYTOKINE_PATHWAYS
CASCADE:TGFB

References
PMID:24132110
TGFB1, TGFB2, TGFB3 ligands bind to the type 2 TGFβ receptor (TGFBR2), which causes recruitment and phosphorylation of TGFBR1, resulting in downstream signalling activation.

Modifications:
In compartment: INNATE_IMMUNE_CELL_Membrane
  1. TGFBR1@INNATE_IMMUNE_CELL_Membrane map
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Membrane
  1. TGFB*:​TGFBR1:​TGFBR2@INNATE_IMMUNE_CELL_Membrane map
Participates in reactions:
As Reactant or Product:
  1. TGFBR1@INNATE_IMMUNE_CELL_Membrane map + TGFBR2@INNATE_IMMUNE_CELL_Membrane map + TGFB*@default map → map TGFB*:​TGFBR1:​TGFBR2@INNATE_IMMUNE_CELL_Membrane map
As Catalyser:
  1. gCCL5@INNATE_IMMUNE_CELL_Cytosol map → map rCCL5@INNATE_IMMUNE_CELL_Cytosol map
  2. SMAD3@INNATE_IMMUNE_CELL_Cytosol map → map SMAD3|​pho@INNATE_IMMUNE_CELL_Cytosol map
  3. SMAD2@INNATE_IMMUNE_CELL_Cytosol map → map SMAD2|​pho@INNATE_IMMUNE_CELL_Cytosol map
  4. O_sub_2_endsub_@INNATE_IMMUNE_CELL_Cytosol map → map O_sub_2_endsub__super_-_endsuper_@INNATE_IMMUNE_CELL_Cytosol map
  5. gCCL3@INNATE_IMMUNE_CELL_Cytosol map → map rCCL3@INNATE_IMMUNE_CELL_Cytosol map
  6. gCCL2@INNATE_IMMUNE_CELL_Cytosol map → map rCCL2@INNATE_IMMUNE_CELL_Cytosol map