Simple molecule GTP

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Modifications:
In compartment: Cell membrane

1. GTP@Cell membrane

In compartment: Rab7 vesicular structure

1. GTP@Rab7 vesicular structure

Participates in complexes:
In compartment: Cell membrane

1. GTP:​eEF2@Cell membrane
2. GTP:​eEF1A@Cell membrane
3. GTP:​eEF2|​T56_pho@Cell membrane
4. GTP:​eEF1A|​T431_pho@Cell membrane
5. GTP:​PLD1:​Rheb@Cell membrane
6. FKBP38:​GTP:​Rheb@Cell membrane
7. GTP:​Ribosome 80S complex:​eEF2@Cell membrane
8. GTP:​aminoacyl-tRNAs:​eEF1A|​T431_pho@Cell membrane
9. (GTP:​eIF2_alpha:​eIF2_beta:​eIF2_gamma)|​active@Cell membrane
10. GTP:​RagA:​RagB:​RagC:​RagD@Cell membrane
11. GTP:​Met-tRNAi:​eIF2_alpha:​eIF2_beta:​eIF2_gamma@Cell membrane
12. GTP:​Raptor|​S722_pho|​S719_pho|​S721_pho|​S863_pho:​RhebL1:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane
13. GTP:​RagA:​RagB:​RagC:​RagD:​mTORC1@Cell membrane
14. GTP:​Met-tRNAi:​eIF2_alpha:​eIF2_beta:​eIF2_gamma:​rpS6/40S subunit|​S235_pho|​S236_pho|​S240_pho|​S244_pho|​S247_pho@Cell membrane
15. FKBP38:​GTP:​Raptor|​S722_pho|​S719_pho|​S721_pho|​S863_pho:​Rheb:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane

In compartment: Rab7 vesicular structure

1. GTP:​Rheb@Rab7 vesicular structure
2. GTP:​RhebL1@Rab7 vesicular structure
3. GTP:​RagA:​RagB:​RagC:​RagD:​Raptor:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Rab7 vesicular structure
4. GTP:​RagA:​RagB:​RagC:​RagD:​Raptor:​Rheb:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Rab7 vesicular structure

Participates in reactions:
As Reactant or Product:

1. FKBP38:​GTP:​Raptor|​S722_pho|​S719_pho|​S721_pho|​S863_pho:​Rheb:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane → SREBP@Cell membrane
2. FKBP38:​GTP:​Raptor|​S722_pho|​S719_pho|​S721_pho|​S863_pho:​Rheb:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane → Lipin-1|​pho@Cell membrane
3. GTP:​Rheb@Rab7 vesicular structure + FKBP38:​Raptor:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane → FKBP38:​GTP:​Raptor|​S722_pho|​S719_pho|​S721_pho|​S863_pho:​Rheb:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane
4. FKBP38:​Raptor:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane → FKBP38:​GTP:​Raptor|​S722_pho|​S719_pho|​S721_pho|​S863_pho:​Rheb:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane
5. GTP:​Rheb@Rab7 vesicular structure + PLD1@Cell membrane → GTP:​PLD1:​Rheb@Cell membrane
6. GTP:​PLD1:​Rheb@Cell membrane → PA@Cell membrane
7. Raptor@Cell membrane → FKBP38:​GTP:​Raptor|​S722_pho|​S719_pho|​S721_pho|​S863_pho:​Rheb:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane
8. GTP:​Rheb@Rab7 vesicular structure → GDP:​Rheb@Rab7 vesicular structure
9. GDP:​eIF2_alpha:​eIF2_beta:​eIF2_gamma@Cell membrane + GTP@Cell membrane → (GTP:​eIF2_alpha:​eIF2_beta:​eIF2_gamma)|​active@Cell membrane + GDP@Cell membrane
10. (GTP:​eIF2_alpha:​eIF2_beta:​eIF2_gamma)|​active@Cell membrane + Met-tRNAi@Cell membrane → GTP:​Met-tRNAi:​eIF2_alpha:​eIF2_beta:​eIF2_gamma@Cell membrane
11. rpS6/40S subunit|​S235_pho|​S236_pho|​S240_pho|​S244_pho|​S247_pho@Cell membrane + GTP:​Met-tRNAi:​eIF2_alpha:​eIF2_beta:​eIF2_gamma@Cell membrane → GTP:​Met-tRNAi:​eIF2_alpha:​eIF2_beta:​eIF2_gamma:​rpS6/40S subunit|​S235_pho|​S236_pho|​S240_pho|​S244_pho|​S247_pho@Cell membrane
12. GTP:​Met-tRNAi:​eIF2_alpha:​eIF2_beta:​eIF2_gamma:​rpS6/40S subunit|​S235_pho|​S236_pho|​S240_pho|​S244_pho|​S247_pho@Cell membrane + GDP@Cell membrane → GDP:​eIF2_alpha:​eIF2_beta:​eIF2_gamma:​rpS6/40S subunit|​S235_pho|​S236_pho|​S240_pho|​S244_pho|​S247_pho@Cell membrane + GTP@Cell membrane
13. GDP:​eIF2_alpha:​eIF2_beta:​eIF2_gamma@Cell membrane → (GTP:​eIF2_alpha:​eIF2_beta:​eIF2_gamma)|​active@Cell membrane
14. GDP:​eEF1A|​T431_pho@Cell membrane + GTP@Cell membrane → GTP:​eEF1A|​T431_pho@Cell membrane + GDP@Cell membrane
15. GTP:​eEF1A@Cell membrane → GDP:​eEF1A|​T431_pho@Cell membrane
16. raminoacyl-tRNAs@Cell membrane + GTP:​eEF1A|​T431_pho@Cell membrane → GTP:​aminoacyl-tRNAs:​eEF1A|​T431_pho@Cell membrane
17. GDP:​eEF2@Cell membrane + GTP@Cell membrane → GTP:​eEF2@Cell membrane + GDP@Cell membrane
18. GTP:​eEF2@Cell membrane → GTP:​eEF2|​T56_pho@Cell membrane
19. Ribosome 80S complex@Cell membrane + GTP:​eEF2@Cell membrane → GTP:​Ribosome 80S complex:​eEF2@Cell membrane
20. GTP:​Ribosome 80S complex:​eEF2@Cell membrane → mRNA translation@Cell membrane
21. FKBP38:​GTP:​Raptor|​S722_pho|​S719_pho|​S721_pho|​S863_pho:​Rheb:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane + 4EBP-1:​S6K1|​S371_pho|​S411_pho|​S418_pho|​T421_pho|​S424_pho|​S17_pho:​eIF3:​eIF4E:​m7GTP:​mRNA@Cell membrane → 4EBP-1:​Raptor|​S722_pho|​S719_pho|​S721_pho|​S863_pho:​S6K1|​S371_pho|​S411_pho|​S418_pho|​T421_pho|​S424_pho|​S17_pho:​eIF3:​eIF4E:​m7GTP:​mRNA:​mTOR|​S2481_pho|​S1261_pho@Cell membrane
22. 5'cap-eIF4F-eIF4B-eIF3-PABP:​eIF2-GTP_Met-tRNAi_40S@Cell membrane → GTP:​Ribosome 80S complex:​eEF2@Cell membrane
23. GTP:​Rheb@Rab7 vesicular structure + FKBP38:​Raptor:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane → FKBP38:​GTP:​Raptor|​S722_pho|​S719_pho|​S721_pho|​S863_pho:​Rheb:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane
24. Bnip3@Cell membrane + GTP:​Rheb@Rab7 vesicular structure → Bnip3:​Rheb@Cell membrane
25. GTP:​Rheb@Rab7 vesicular structure → GDP:​Rheb@Rab7 vesicular structure
26. GDP:​Rheb@Rab7 vesicular structure → GTP:​Rheb@Rab7 vesicular structure
27. GTP:​Rheb@Rab7 vesicular structure + GDP@Rab7 vesicular structure → GDP:​Rheb@Rab7 vesicular structure + GTP@Rab7 vesicular structure
28. GDP:​Rheb@Rab7 vesicular structure → GTP:​Rheb@Rab7 vesicular structure
29. FKBP38:​GTP:​Raptor|​S722_pho|​S719_pho|​S721_pho|​S863_pho:​Rheb:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane → Raptor|​S722_pho|​S719_pho|​S721_pho|​S863_pho:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane + FKBP38:​GTP:​Rheb@Cell membrane
30. GDP:​RagA:​RagB:​RagC:​RagD@Cell membrane + GTP@Cell membrane → GTP:​RagA:​RagB:​RagC:​RagD@Cell membrane + GDP@Cell membrane
31. Raptor:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane + GTP:​RagA:​RagB:​RagC:​RagD@Cell membrane → GTP:​RagA:​RagB:​RagC:​RagD:​mTORC1@Cell membrane
32. GTP:​RagA:​RagB:​RagC:​RagD:​mTORC1@Cell membrane → GTP:​RagA:​RagB:​RagC:​RagD:​Raptor:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Rab7 vesicular structure
33. FKBP38:​GTP:​Raptor|​S722_pho|​S719_pho|​S721_pho|​S863_pho:​Rheb:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane → mTOR|​S2481_pho|​S1261_pho|​active@Nucleus
34. GTP:​RhebL1@Rab7 vesicular structure + GDP@Rab7 vesicular structure → GDP:​RhebL1@Rab7 vesicular structure + GTP@Rab7 vesicular structure
35. GTP:​RhebL1@Rab7 vesicular structure + Raptor|​S722_pho|​S719_pho|​S721_pho|​S863_pho:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane → GTP:​Raptor|​S722_pho|​S719_pho|​S721_pho|​S863_pho:​RhebL1:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane
36. FKBP38:​Raptor:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane → FKBP38:​GTP:​Raptor|​S722_pho|​S719_pho|​S721_pho|​S863_pho:​Rheb:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane
37. GTP:​Rheb@Rab7 vesicular structure + GTP:​RagA:​RagB:​RagC:​RagD:​Raptor:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Rab7 vesicular structure → GTP:​RagA:​RagB:​RagC:​RagD:​Raptor:​Rheb:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Rab7 vesicular structure
38. FKBP38:​GTP:​Raptor|​S722_pho|​S719_pho|​S721_pho|​S863_pho:​Rheb:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane → Raptor|​S722_pho|​S792_pho|​S719_pho|​S721_pho|​S863_pho@Cell membrane
39. FKBP38:​Raptor:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane → FKBP38:​GTP:​Raptor|​S722_pho|​S719_pho|​S721_pho|​S863_pho:​Rheb:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane

As Catalyser:

1. GTP:​Rheb@Rab7 vesicular structure + FKBP38:​Raptor:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane → FKBP38:​GTP:​Raptor|​S722_pho|​S719_pho|​S721_pho|​S863_pho:​Rheb:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane
2. GTP:​Rheb@Rab7 vesicular structure + PLD1@Cell membrane → GTP:​PLD1:​Rheb@Cell membrane
3. mTOR@Cell membrane → mTOR|​S1261_pho@Cell membrane
4. S6K1|​S371_pho|​S411_pho|​S418_pho|​T421_pho|​S424_pho|​S17_pho@Cell membrane → S6K1|​T389_pho|​S371_pho|​S411_pho|​S418_pho|​T421_pho|​S424_pho|​S17_pho|​active@Cell membrane
5. S6K1|​S17_pho@Cell membrane → S6K1|​S371_pho|​S411_pho|​S418_pho|​T421_pho|​S424_pho|​S17_pho@Cell membrane
6. 4EBP-1@Cell membrane → 4EBP-1|​T37_pho|​T46_pho@Cell membrane
7. gDEPTOR@Nucleus → rDEPTOR@Cell membrane
8. DEPTOR:​Raptor:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane → DEPTOR|​pho:​Raptor:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane
9. 4EBP-1|​T37_pho|​T46_pho@Cell membrane → 4EBP-1|​T37_pho|​T46_pho|​S70_pho@Cell membrane
10. 4EBP-1|​T37_pho|​T46_pho|​S70_pho@Cell membrane → 4EBP-1|​T37_pho|​T46_pho|​S65_pho|​S70_pho@Cell membrane
11. eIF4G@Cell membrane → eIF4G|​S1108_pho|​S1148_pho|​S1192_pho@Cell membrane
12. Ribosome 80S complex@Cell membrane + GTP:​eEF2@Cell membrane → GTP:​Ribosome 80S complex:​eEF2@Cell membrane
13. eEF2K|​S500_pho|​active@Cell membrane → eEF2K|​S359_pho|​S500_pho@Cell membrane
14. Ca_sub_2+:​Calmodulin:​eEF2K@Cell membrane → Ca_sub_2+:​Calmodulin:​eEF2K|​S78_pho@Cell membrane
15. r5'-TOP mRNA@Cell membrane → 5'-TOP-derived proteins@Cell membrane
16. cdc2:​cyclin B@Cell membrane → cdc2:​cyclin B@Cell membrane
17. 4EBP-1:​eIF4E:​m7GTP:​mRNA@Cell membrane → 4EBP-1|​T37_pho|​T46_pho|​S65_pho|​S70_pho:​eIF4E:​m7GTP:​mRNA@Cell membrane
18. PP2A@Cell membrane → PP2A|​pho@Cell membrane
19. Pol I:​TIF-1A|​S633_pho|​S649_pho|​S44_pho|​S170_pho|​S172_pho:​TIF-1B/SL1:​UBF|​pho|​ace|​S484_pho|​S388_pho|​hm2:​rDNA@Nucleus → rrRNA@Nucleus
20. URI@Cell membrane → URI|​pho@Cell membrane
21. PRAS40:​mTORC1@Cell membrane → PRAS40|​S221_pho|​S183_pho|​S212_pho:​mTORC1@Cell membrane
22. Raptor@Cell membrane → FKBP38:​GTP:​Raptor|​S722_pho|​S719_pho|​S721_pho|​S863_pho:​Rheb:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane
23. DEPTOR:​Rictor:​Sin1.1:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane → DEPTOR|​pho:​Rictor:​Sin1.1:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane
24. rPDGRF@Nucleus → PDGFR_beta@Cell membrane
25. PPR5L:​Rictor:​Sin1.1:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane → PPR5L|​pho:​Rictor:​Sin1.1:​mLST8:​mTOR|​S2481_pho|​S1261_pho@Cell membrane
26. SGK1@Cell membrane → SGK1|​S422_pho@Cell membrane
27. ATG13:​FIP200:​ULK1/2@Cell membrane → ATG13|​pho:​FIP200:​ULK1/2|​pho@Cell membrane
28. ATG13:​FIP200:​ULK1/2@Cell membrane → ATG13|​pho:​FIP200:​ULK1/2|​pho@Cell membrane