Simple molecule PI3,4,5-P_sub_3
Modifications:
In compartment: Cell membrane
- PI3,4,5-P_sub_3@Cell membrane
Participates in complexes:
In compartment: Cell membrane
- AKT:PI3,4,5-P_sub_3@Cell membrane
- PDK1:PI3,4,5-P_sub_3@Cell membrane
- AKT|T450_pho:PI3,4,5-P_sub_3@Cell membrane
- AKT|S473_pho|T450_pho:PI3,4,5-P_sub_3@Cell membrane
- AKT|T308_pho|T450_pho:PI3,4,5-P_sub_3@Cell membrane
- AKT|T308_pho|S473_pho|T450_pho:PI3,4,5-P_sub_3@Cell membrane
Participates in reactions:
As Reactant or Product:- AKT|T450_pho:PI3,4,5-P_sub_3@Cell membrane
→
AKT|S473_pho|T450_pho:PI3,4,5-P_sub_3@Cell membrane
- PI4,5-P_sub_2@Cell membrane
→
PI3,4,5-P_sub_3@Cell membrane
- PI3,4,5-P_sub_3@Cell membrane
→
PI4,5-P_sub_2@Cell membrane
- PI3,4,5-P_sub_3@Cell membrane
+ PDK1@Cell membrane
→
PDK1:PI3,4,5-P_sub_3@Cell membrane
- 14-3-3_beta:ERK1/2|T202_pho|Y204_pho:PDK1:RSK1/2|S352_pho|S221_pho|S369_pho|T562_pho|S154_pho|T348_pho|S721_pho@Cell membrane
→
RSK1/2|S352_pho|S221_pho|S369_pho|T562_pho|T348_pho|S721_pho|active@Cell membrane
+ PDK1:PI3,4,5-P_sub_3@Cell membrane
- AKT|T450_pho@Cell membrane
+ PI3,4,5-P_sub_3@Cell membrane
→
AKT|T450_pho:PI3,4,5-P_sub_3@Cell membrane
- AKT|S473_pho|T450_pho:PI3,4,5-P_sub_3@Cell membrane
→
AKT|T308_pho|S473_pho|T450_pho:PI3,4,5-P_sub_3@Cell membrane
- PDGF:PDGFR_beta@Cell membrane
→
AKT|T308_pho|S473_pho|T450_pho:PI3,4,5-P_sub_3@Cell membrane
- AKT|T450_pho:PI3,4,5-P_sub_3@Cell membrane
→
AKT|S473_pho|T450_pho:PI3,4,5-P_sub_3@Cell membrane
- AKT|T450_pho:PI3,4,5-P_sub_3@Cell membrane
→
AKT|T308_pho|T450_pho:PI3,4,5-P_sub_3@Cell membrane
- AKT|T308_pho|S473_pho|T450_pho:PI3,4,5-P_sub_3@Cell membrane
→
AKT:PI3,4,5-P_sub_3@Cell membrane
As Catalyser:- S6K1|T389_pho|S371_pho|S411_pho|S418_pho|T421_pho|S424_pho|S17_pho|active@Cell membrane
→
S6K1|T229_pho|T389_pho|S371_pho|S411_pho|S418_pho|T421_pho|S424_pho|S17_pho|active@Cell membrane
- PDK1@Cell membrane
→
PDK1@Cell membrane
- AKT|T450_pho@Cell membrane
→
AKT|T450_pho@Cell membrane
- TSC2|S1798_pho@Nucleus
→
TSC2|S981_pho|S939_pho|S1798_pho|T1462_pho@Cell membrane
- GSK3alpha/beta@Cell membrane
→
GSK3alpha/beta|S21/9_pho@Cell membrane
- TSC1:TSC2@Endomembrane
→
TSC1:TSC2|S981_pho|S939_pho|T1462_pho@Endomembrane
- PRAS40:mTORC1@Cell membrane
→
PRAS40|T246_pho:mTORC1@Cell membrane
- AKT|S473_pho|T450_pho:PI3,4,5-P_sub_3@Cell membrane
→
AKT|T308_pho|S473_pho|T450_pho:PI3,4,5-P_sub_3@Cell membrane
- AKT|T450_pho:PI3,4,5-P_sub_3@Cell membrane
→
AKT|T308_pho|T450_pho:PI3,4,5-P_sub_3@Cell membrane
- FoxO1/3a@Nucleus
→
FoxO1/3a|S253_pho|T24/32_pho@Nucleus
- p27|S10_pho@Cell membrane
→
p27|S10_pho|T198_pho@Cell membrane
- p27|S10_pho|T198_pho@Cell membrane
→
p27|S10_pho|T198_pho|T157_pho@Cell membrane